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Full Chemical Name: JWH-018

Systematic IUPAC Name Naphthalen-1-yl-(1-pentylindol-3-yl)meth anone

CAS Number 209414-07-3

ChemSpider Number 8558143

Molecular Formula C24H23NO

Molecular Mass 341.45 g/mo

What is JWH 018?


JWH 018 is a mildly selective agonist of the peripheral cannabinoid (CB2) receptor, derived from the aminoalkylindole WIN 55,212-2. The Ki values for binding central cannabinoid (CB1) and CB2 receptors are 9.0 and 2.94 nM, respectively, for a CB1:CB2 ratio of 3.06.1 Its effects on suppression of spontaneous activity, maximum possible antinociceptive effect in the tail-flick assay, and rectal temperature are comparable to those of WIN 55,212-2 when tested in rats.


It is a research chemical that belongs to the naphthoylindole family. JWH-081 as all the other research chemicals in the JWH group is a synthetic cannabinoid with analgesic effects.Its full chemical name is 4-methoxynaphthalen- 1-yl- (1-pentylindol- 3-yl)methanone with chemical formula as C25H25NO2 and molecular mass 371.47 g/mol.

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